This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most maligt tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
CD221; IGF-I receptor; IGF-I receptor insulin-like growth factor I receptor soluble IGF1R variant 1 soluble IGF1R variant 2 CD221; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2
Cat # 11305333
100 µL
Cat # 11385313
100 µL
Cat # 10189492
100 µg
Cat # 11384923
500µL
Cat # 10595294
100 µg
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